The compound's anti-inflammatory properties contribute to joint recovery by reducing synovial inflammation, a primary driver of pain and restricted movement
Orphanet journal of rare diseases 2020
Exercise generates oxidative stress as a natural byproduct of increased metabolism, and adequate antioxidant defenses help mitigate this stress while supporting recovery processes
Superoxide combines with NO to form peroxynitrite that oxidizes BH 4 and destabilizes eNOS to produce more superoxide 22, 24, 25 thus, further enhancing the development of oxidative stress
Activates AMPK (The Metabolic Master Switch) MOTS-C activates AMP-activated protein kinase (AMPK) often called the metabolic master switch. AMPK activation: Increases glucose uptake into cells (improving insulin sensitivity) Enhances fat oxidation (fat burning) Increases mitochondrial biogenesis (creating new, healthy mitochondria) Reduces inflammation Promotes autophagy (cellular cleanup and renewal) This is the same pathway activated by exercise and calorie restriction two of the most powerful interventions for metabolic health and longevity
This complex is then escorted across the inner membrane by a specific transporter protein
